SREBP

The gene Sterol regulatory element binding protein is referred to in FlyBase by the symbol DmelSREBP (CG8522, FBgn0261283). It is a protein_coding_gene from Dmel. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 3L:19793935..19798979. Its molecular function is described by: DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding; protein dimerization activity. It is involved in the biological process described with 8 unique terms, many of which group under: regulation of catabolic process; anion homeostasis; developmental process; regulation of lipid biosynthetic process; cell morphogenesis. 35 alleles are reported. The phenotypes of these alleles manifest in: plasma membrane bounded cell projection; organelle; endomembrane system; adult circulatory system; cell body. The phenotypic classes of alleles include: increased mortality; increased mortality during development; phenotype; size defective. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed within 00-06 and 18-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period, in stages of adults of both sexes.

Sterol regulatory element binding protein

Source FlyBase

Drosophila melanogaster [tax_id: 7227]

dm6