SVIL

Information SVIL

Description

This gene encodes a bipartite protein with distinct amino- and carboxy-terminal domains. The amino-terminus contains nuclear localization signals and the carboxy-terminus contains numerous consecutive sequences with extensive similarity to proteins in the gelsolin family of actin-binding proteins, which cap, nucleate, and/or sever actin filaments. The gene product is tightly associated with both actin filaments and plasma membranes, suggesting a role as a high-affinity link between the actin cytoskeleton and the membrane. The encoded protein appears to aid in both myosin II assembly during cell spreading and disassembly of focal adhesions. Several transcript variants encoding different isoforms of supervillin have been described. [provided by RefSeq, Apr 2016]

Full Name

supervillin

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
1
Biotypes
1
Peaks
127
Non-redundant peaks
127

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
6840
Official Gene Name
SVIL
JASPAR
Ensembl
ENSG00000197321
UniProt
O95425
Genevisible
O95425
RefSeq
NM_001323599
Aliases
All peaks SVIL
Download BED file
Non redundant peaks SVIL
Download BED file
SEQUENCES SVIL
Download FASTA file
DOWNLOAD All ReMap
Got to catalogue

Datasets Table for SVIL

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
SVIL SH-SY5Y B3_SHCTR GEO Homo sapiens GSE58258 127
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks