Scr

Information Scr

Description

The gene Sex combs reduced is referred to in FlyBase by the symbol DmelScr (CG1030, FBgn0003339). It is a protein_coding_gene from Dmel. It has 5 annotated transcripts and 5 polypeptides (4 unique). Gene sequence location is 3R:6823120..6849981. Its molecular function is described by: sequence-specific DNA binding; RNA polymerase II transcription regulatory region sequence-specific DNA binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific; protein homodimerization activity. It is involved in the biological process described with 6 unique terms, many of which group under: anatomical structure development; developmental process; multicellular organism development; system development; pattern specification process. 158 alleles are reported. The phenotypes of these alleles manifest in: central brain; embryonic/larval endocrine system; wing; maxillary palpus; head capsule. The phenotypic classes of alleles include: lethal; phenotype; increased mortality; increased mortality during development. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed within 06-24 hour embryonic stages, during late larval stages, during early pupal stages.

Full Name

Sex combs reduced

Source FlyBase

Species

Drosophila melanogaster [tax_id: 7227]

Genome

dm6

ReMap Statistics

Datasets
2
Biotypes
1
Peaks
21,766
Non-redundant peaks
13,531

TF Classification

Familly
Homeo domain factors
Sub Familly
HOX-related factors

Source JASPAR

External IDs

NCBI Gene
40833
Official Gene Name
Scr
JASPAR
MA0203.1
Ensembl
FBgn0003339
UniProt
P09077
Genevisible
P09077
RefSeq
NM_206443
Aliases
Scr
All peaks Scr
Download BED file
Non redundant peaks Scr
Download BED file
SEQUENCES Scr
Download FASTA file
DOWNLOAD All ReMap
Got to catalogue

Datasets Table for Scr

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
Scr Kc167 Hth GEO Drosophila melanogaster GSE122574 10,227
Scr Kc167 GEO Drosophila melanogaster GSE122574 11,539
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks