Sin3A

The gene Sin3A is referred to in FlyBase by the symbol DmelSin3A (CG8815, FBgn0022764). It is a protein_coding_gene from Dmel. It has 10 annotated transcripts and 10 polypeptides (7 unique). Gene sequence location is 2R:12575240..12592917. Its molecular function is described by: transcription corepressor activity; protein heterodimerization activity; chromatin binding; histone deacetylase activity. It is involved in the biological process described with 13 unique terms, many of which group under: regulation of developmental process; negative regulation of signal transduction; protein deacylation; regulation of mitotic cell cycle; cell-cell signaling. 63 alleles are reported. The phenotypes of these alleles manifest in: somatic muscle; posterior crossvein; presumptive embryonic/larval muscle system; imaginal tissue; adult sense organ. The phenotypic classes of alleles include: size defective; phenotype; increased mortality during development; some die during P-stage. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages, in adult female stages.

Sin3A

Source FlyBase

Drosophila melanogaster [tax_id: 7227]

dm6