Su-Tpl

The gene Suppressor of Triplolethal is referred to in FlyBase by the symbol DmelSu(Tpl) (CG32217, FBgn0014037). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3L:19889120..19909410. Its molecular function is described by: protein binding; RNA polymerase binding; chromatin binding. It is involved in the biological process described with: regulation of DNA-templated transcription in response to stress; wing disc dorsal/ventral pattern formation; snRNA transcription by RNA polymerase II; neuronal stem cell population maintenance; positive regulation of transcription elongation from RNA polymerase II promoter. 45 alleles are reported. The phenotypes of these alleles manifest in: neuroblast; somatic precursor cell; embryonic/larval brain; mechanosensory sensory organ; peripheral nervous system. The phenotypic classes of alleles include: partially lethal; phenotype; increased mortality during development; increased mortality. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression. Peak expression observed at stages throughout embryogenesis, in adult female stages.

Su(Tpl)

Source FlyBase

Drosophila melanogaster [tax_id: 7227]

dm6