Su-var-2-10

The gene Suppressor of variegation 2-10 is referred to in FlyBase by the symbol DmelSu(var)2-10 (CG8068, FBgn0003612). It is a protein_coding_gene from Dmel. It has 14 annotated transcripts and 14 polypeptides (all unique). Gene sequence location is 2R:9116122..9122000. Its molecular function is described by: SUMO ligase activity; zinc ion binding; RNA polymerase II transcription factor binding; STAT family protein binding; transcription coregulator activity. It is involved in the biological process described with 12 unique terms, many of which group under: cellular component organization or biogenesis; cellular nitrogen compound metabolic process; anatomical structure development; cellular response to stress; negative regulation of receptor signaling pathway via JAK-STAT. 34 alleles are reported. The phenotypes of these alleles manifest in: adult head sensillum; adult external thorax; neuroblast; ovariole; gut. The phenotypic classes of alleles include: phenotype; size defective; increased mortality; melanotic mass phenotype. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages, in adult female stages.

Suppressor of variegation 2-10

Source FlyBase

Drosophila melanogaster [tax_id: 7227]

dm6