T
Information T
- Description
The protein encoded by this gene is an embryonic nuclear transcription factor that binds to a specific DNA element, the palindromic T-site. It binds through a region in its N-terminus, called the T-box, and effects transcription of genes required for mesoderm formation and differentiation. The protein is localized to notochord-derived cells. Variation in this gene was associated with susceptibility to neural tube defects and chordoma. A mutation in this gene was found in a family with sacral agenesis with vertebral anomalies. [provided by RefSeq, Sep 2018]
- Full Name
T-box transcription factor T
Source NCBI
- Species
Homo sapiens [tax_id: 9606]
- Genome
hg38
ReMap Statistics
- Datasets
- 2
- Biotypes
- 1
- Peaks
- 57,059
- Non-redundant peaks
- 50,485
TF Classification
- Super Class
- NA
- Class
- NA
- Familly
- NA
- Sub Familly
- NA
Source TFClass
External IDs
- NCBI Gene
- 6862
- Official Gene Name
- TBXT
- JASPAR
- MA0009
- Ensembl
- ENSG00000164458
- UniProt
- O15178
- Genevisible
- O15178
- RefSeq
- NM_001270484
- Aliases
- SAVA; T; TFT
Datasets Table for T
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| T | H9 | ENDODERM | GEO | Homo sapiens | GSE60606 | 23,419 | ||
| T | H9 | MESODERM | GEO | Homo sapiens | GSE60606 | 33,640 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |