TARDBP

Information TARDBP

Description

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq, Jul 2008]

Full Name

TAR DNA binding protein

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
10
Biotypes
5
Peaks
227,432
Non-redundant peaks
135,300

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
23435
Official Gene Name
TARDBP
JASPAR
Ensembl
ENSG00000120948
UniProt
Q13148
Genevisible
Q13148
RefSeq
NM_007375
Aliases
ALS10; TDP-43

External links
All peaks TARDBP
Download BED file
Non redundant peaks TARDBP
Download BED file
SEQUENCES TARDBP
Download FASTA file
DOWNLOAD All ReMap
Got to catalogue

Datasets Table for TARDBP

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
TARDBP Hep-G2 GEO Homo sapiens GSE120104 14,503
TARDBP K-562 GEO Homo sapiens GSE120104 37,547
TARDBP MCF-7 ENCODE Homo sapiens ENCSR801SWX 17,067
TARDBP K-562 ENCODE Homo sapiens ENCSR033VAZ 9,103
TARDBP K-562 ENCODE Homo sapiens ENCSR429XTR 33,194
TARDBP K-562 ENCODE Homo sapiens ENCSR353HEP 13,399
TARDBP Hep-G2 ENCODE Homo sapiens ENCSR145CXH 23,968
TARDBP HEK293T ENCODE Homo sapiens ENCSR753GIA 1,212
TARDBP GM12878 ENCODE Homo sapiens ENCSR412QBS 69,129
TARDBP GM12878 ENCODE Homo sapiens ENCSR016UEH 8,310
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks