TBP

Information TBP

Description

General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Component of a BRF2-containing transcription factor complex that regulates transcription mediated by RNA polymerase III. Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (pre-initiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promoter. SL1 is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. {ECO:0000250|UniProtKB:P20226}.(Source UnitProtKB).

Full Name

TATA box binding protein

Source UniprotKB

Species

Mus musculus [tax_id: 10090]

Genome

mm10

ReMap Statistics

Datasets
17
Biotypes
7
Peaks
304,278
Non-redundant peaks
148,620

TF Classification

Familly
NA
Sub Familly
NA

Source JASPAR

External IDs

NCBI Gene
21374
Official Gene Name
Tbp
JASPAR
MGI
MGI:101838
Ensembl
ENSMUSG00000014767
UniProt
P29037
Genevisible
P29037
RefSeq
NM_013684
Aliases
GTF2D1; Gtf2d; SCA17; TFIID
All peaks TBP
Download BED file
Non redundant peaks TBP
Download BED file
SEQUENCES TBP
Download FASTA file
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Datasets Table for TBP

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
TBP CH12-LX ENCODE Mus musculus ENCSR000ERP 25,563
TBP MEL ENCODE Mus musculus ENCSR000EUB 37,770
TBP liver TAF4-hep GEO Mus musculus GSE57807 6,510
TBP liver ZT2 GEO Mus musculus GSE96773 7,900
TBP RAW264-7 GEO Mus musculus GSE23619 12,697
TBP trophoblast-stem-cell GEO Mus musculus GSE39406 3,793
TBP testis GEO Mus musculus GSE79601 9,792
TBP testis KO GEO Mus musculus GSE79601 9,911
TBP mESC EB8-WT GEO Mus musculus GSE70661 21,726
TBP mESC ES-KO GEO Mus musculus GSE70661 32,134
TBP mESC mitotic GEO Mus musculus GSE109962 8,524
TBP mESC asynchronous GEO Mus musculus GSE109962 32,834
TBP liver ZT10 GEO Mus musculus GSE96773 1,787
TBP liver GEO Mus musculus GSE57807 21,567
TBP mESC B2 GEO Mus musculus GSE22303 24,772
TBP mESC GEO Mus musculus GSE70661 37,617
TBP mESC EB8-KO GEO Mus musculus GSE70661 9,381
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks