TBX6
Information TBX6
- Description
T-box transcription factor that plays an essential role in the determination of the fate of axial stem cells: neural vs mesodermal. Acts in part by down-regulating, a specific enhancer (N1) of SOX2, to inhibit neural development. Seems to play also an essential role in left/right axis determination and acts through effects on Notch signaling around the node as well as through an effect on the morphology and motility of the nodal cilia. {ECO:0000269|PubMed:15545628, ECO:0000269|PubMed:18575602, ECO:0000269|PubMed:21331042, ECO:0000269|PubMed:9490412}.(Source UnitProtKB).
- Full Name
T-box 6
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 1
- Biotypes
- 1
- Peaks
- 33,328
- Non-redundant peaks
- 33,328
TF Classification
- Familly
- NA
- Sub Familly
- NA
Source JASPAR
External IDs
- NCBI Gene
- 21389
- Official Gene Name
- Tbx6
- JASPAR
- MGI
- MGI:102539
- Ensembl
- ENSMUSG00000030699
- UniProt
- P70327
- Genevisible
- P70327
- RefSeq
- Aliases
- rv
Datasets Table for TBX6
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| TBX6 | neuro-mesodermal-progenitors | GEO | Mus musculus | GSE93524 | 33,328 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |