TCOF1

Information TCOF1

Description

This gene encodes a nucleolar protein with a LIS1 homology domain. The protein is involved in ribosomal DNA gene transcription through its interaction with upstream binding factor (UBF). Mutations in this gene have been associated with Treacher Collins syndrome, a disorder which includes abnormal craniofacial development. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]

Full Name

treacle ribosome biogenesis factor 1

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
1
Biotypes
1
Peaks
282
Non-redundant peaks
282

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
6949
Official Gene Name
TCOF1
JASPAR
Ensembl
ENSG00000070814
UniProt
Q13428
Genevisible
Q13428
RefSeq
NM_000356
Aliases
MFD1; TCS; TCS1; treacle
All peaks TCOF1
Download BED file
Non redundant peaks TCOF1
Download BED file
SEQUENCES TCOF1
Download FASTA file
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Datasets Table for TCOF1

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
TCOF1 HeLa GEO Homo sapiens GSE89420 282
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks