TFAM

The gene mitochondrial transcription factor A is referred to in FlyBase by the symbol DmelTFAM (CG4217, FBgn0038805). It is a protein_coding_gene from Dmel. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:20575245..20577010. Its molecular function is described by: DNA-binding transcription factor activity; DNA binding, bending; transcription regulatory region sequence-specific DNA binding. It is involved in the biological process described with: response to oxidative stress; regulation of transcription by RNA polymerase II; positive regulation of transcription, DNA-templated. 16 alleles are reported. The phenotypes of these alleles manifest in: cellular anatomical entity; synapse; cell junction; somatodendritic compartment; intracellular anatomical structure. The phenotypic classes of alleles include: locomotor behavior defective; phenotype; increased mortality; majority die during larval stage. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression. Peak expression observed within 00-18 hour embryonic stages, during early larval stages, in adult female stages.

mitochondrial transcription factor A

Source FlyBase

Drosophila melanogaster [tax_id: 7227]

dm6