TGIF2

Information TGIF2

Description

The protein encoded by this gene is a DNA-binding homeobox protein and a transcriptional repressor, which appears to repress transcription by recruiting histone deacetylases to TGF beta-responsive genes. This gene is amplified and over-expressed in some ovarian cancers. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 1. Read-through transcription also exists between this gene and the neighboring downstream C20orf24 (chromosome 20 open reading frame 24) gene. [provided by RefSeq, Dec 2010]

Full Name

TGFB induced factor homeobox 2

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
1
Biotypes
1
Peaks
15,394
Non-redundant peaks
15,394

TF Classification

Super Class
Helix-turn-helix domains
Class
Homeo domain factors
Familly
TALE-type homeo domain factors
Sub Familly
TGIF

Source TFClass

External IDs

NCBI Gene
60436
Official Gene Name
TGIF2
JASPAR
MA0797
Ensembl
ENSG00000118707
UniProt
Q9GZN2
Genevisible
Q9GZN2
RefSeq
NM_001199513
Aliases
All peaks TGIF2
Download BED file
Non redundant peaks TGIF2
Download BED file
SEQUENCES TGIF2
Download FASTA file
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Datasets Table for TGIF2

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
TGIF2 Hep-G2 ENCODE Homo sapiens ENCSR993LMB 15,394
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks