THRB

Description: The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008]
Full Name: thyroid hormone receptor beta; Source NCBI
Species: Homo sapiens [tax_id: 9606]
Genome: hg38

NCBI Gene: 7068
Official Gene Name: THRB
JASPAR
Ensembl: ENSG00000151090
UniProt: P10828
Genevisible: P10828
RefSeq: NM_000461
Aliases: C-ERBA-2; C-ERBA-BETA; ERBA-BETA; ERBA2; GRTH; NR1A2; PRTH; THR1; THRB1; THRB2

All peaks THRB

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Non redundant peaks THRB

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SEQUENCES THRB

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Got to catalogue

Target name	Target modification	Ecotype/Strain	Biotype	Biotype modification	Source	Species	Experiment	Peaks
THRB			Hep-G2		ENCODE	Homo sapiens	ENCSR430JGJ	43,609
Target name	Target modification	Ecotype/Strain	Biotype	Biotype modification	Source	Species	Experiment	Peaks