TOP1

Information TOP1

Description

This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22. [provided by RefSeq, Jul 2008]

Full Name

DNA topoisomerase I

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
3
Biotypes
2
Peaks
13,939
Non-redundant peaks
10,300

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
7150
Official Gene Name
TOP1
JASPAR
Ensembl
ENSG00000198900
UniProt
P11387
Genevisible
P11387
RefSeq
NM_003286
Aliases
TOPI
All peaks TOP1
Download BED file
Non redundant peaks TOP1
Download BED file
SEQUENCES TOP1
Download FASTA file
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Datasets Table for TOP1

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
TOP1 LNCaP DHT GEO Homo sapiens GSE63202 8,540
TOP1 LNCaP GEO Homo sapiens GSE63202 5,219
TOP1 HCT-116 JQ1 GEO Homo sapiens GSE57628 180
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks