TRPS1

Information TRPS1

Description

This gene encodes a transcription factor that represses GATA-regulated genes and binds to a dynein light chain protein. Binding of the encoded protein to the dynein light chain protein affects binding to GATA consensus sequences and suppresses its transcriptional activity. Defects in this gene are a cause of tricho-rhino-phalangeal syndrome (TRPS) types I-III. [provided by RefSeq, Jul 2008]

Full Name

transcriptional repressor GATA binding 1

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
6
Biotypes
2
Peaks
80,158
Non-redundant peaks
57,388

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
7227
Official Gene Name
TRPS1
JASPAR
Ensembl
ENSG00000104447
UniProt
Q9UHF7
Genevisible
Q9UHF7
RefSeq
NM_001282902
Aliases
GC79; LGCR
All peaks TRPS1
Download BED file
Non redundant peaks TRPS1
Download BED file
SEQUENCES TRPS1
Download FASTA file
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Datasets Table for TRPS1

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
TRPS1 MCF-7 siNT GEO Homo sapiens GSE133072 5,969
TRPS1 MCF-7 siGATA3 GEO Homo sapiens GSE133072 1,486
TRPS1 MCF-7 GEO Homo sapiens GSE133072 45,498
TRPS1 T-47D GEO Homo sapiens GSE107013 20,767
TRPS1 T-47D GEO Homo sapiens GSE114213 2,257
TRPS1 MCF-7 GEO Homo sapiens GSE107013 4,181
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks