U2AF2

Information U2AF2

Description

U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the U2AF large subunit which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an Arg/Ser-rich domain necessary for splicing. The large subunit binds to the polypyrimidine tract of introns early during spliceosome assembly. Multiple transcript variants have been detected for this gene, but the full-length natures of only two have been determined to date. [provided by RefSeq, Jul 2008]

Full Name

U2 small nuclear RNA auxiliary factor 2

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
2
Biotypes
1
Peaks
19,278
Non-redundant peaks
13,935

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
11338
Official Gene Name
U2AF2
JASPAR
Ensembl
ENSG00000063244
UniProt
P26368
Genevisible
P26368
RefSeq
NM_001012478
Aliases
U2AF65
All peaks U2AF2
Download BED file
Non redundant peaks U2AF2
Download BED file
SEQUENCES U2AF2
Download FASTA file
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Datasets Table for U2AF2

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
U2AF2 Hep-G2 GEO Homo sapiens GSE120104 13,356
U2AF2 Hep-G2 ENCODE Homo sapiens ENCSR991ADX 5,922
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks