UBTF

Information UBTF

Description

This gene encodes a member of the HMG-box DNA-binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre-rRNA processing, and its activity is regulated by both phosphorylation and acetylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3, 11 and X and the long arm of chromosome 11. [provided by RefSeq, Aug 2011]

Full Name

upstream binding transcription factor

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
6
Biotypes
4
Peaks
57,261
Non-redundant peaks
42,690

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
7343
Official Gene Name
UBTF
JASPAR
Ensembl
ENSG00000108312
UniProt
P17480
Genevisible
P17480
RefSeq
NM_001076683
Aliases
CONDBA; NOR-90; UBF; UBF-1; UBF1; UBF2
All peaks UBTF
Download BED file
Non redundant peaks UBTF
Download BED file
SEQUENCES UBTF
Download FASTA file
DOWNLOAD All ReMap
Got to catalogue

Datasets Table for UBTF

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
UBTF K-562 ENCODE Homo sapiens ENCSR000EFW 13,830
UBTF K-562 ENCODE Homo sapiens ENCSR000EFZ 36,905
UBTF GM12878 ENCODE Homo sapiens ENCSR459FTB 5,596
UBTF hESC activinA GEO Homo sapiens GSE76586 261
UBTF hESC GEO Homo sapiens GSE76586 390
UBTF HeLa-S3 ENCODE Homo sapiens ENCSR634ZGP 279
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks