VDR
Information VDR
- Description
Nuclear receptor for calcitriol, the active form of vitamin D3 which mediates the action of this vitamin on cells (By similarity). Enters the nucleus upon vitamin D3 binding where it forms heterodimers with the retinoid X receptor/RXR (By similarity). The VDR-RXR heterodimers bind to specific response elements on DNA and activate the transcription of vitamin D3-responsive target genes (By similarity). Plays a central role in calcium homeostasis (By similarity). {ECO:0000250|UniProtKB:P11473, ECO:0000250|UniProtKB:P13053}.(Source UnitProtKB).
- Full Name
vitamin D (1,25-dihydroxyvitamin D3) receptor
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 24
- Biotypes
- 8
- Peaks
- 411,037
- Non-redundant peaks
- 187,038
TF Classification
- Familly
- Nuclear receptors with C4 zinc fingers
- Sub Familly
- Thyroid hormone receptor-related factors (NR1)
Source JASPAR
External IDs
- NCBI Gene
- 22337
- Official Gene Name
- Vdr
- JASPAR
- MA0693.1
- MGI
- MGI:103076
- Ensembl
- ENSMUSG00000022479
- UniProt
- P48281
- Genevisible
- P48281
- RefSeq
- NM_009504
- Aliases
- Nr1i1
Datasets Table for VDR
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| VDR | peripheral-blood-monocyte | GEO | Mus musculus | GSE133025 | 26,763 | |||
| VDR | peripheral-blood-monocyte | veh | GEO | Mus musculus | GSE133025 | 4,089 | ||
| VDR | IDG-SW3 | GEO | Mus musculus | GSE54782 | 7,189 | |||
| VDR | IDG-SW3 | veh | GEO | Mus musculus | GSE54782 | 610 | ||
| VDR | macrophage | GEO | Mus musculus | GSE124722 | 7,283 | |||
| VDR | macrophage | VD3 | GEO | Mus musculus | GSE124722 | 39,169 | ||
| VDR | kidney | GEO | Mus musculus | GSE133025 | 34,834 | |||
| VDR | kidney | M1-IKO_veh | GEO | Mus musculus | GSE133025 | 949 | ||
| VDR | kidney | M1-IKO | GEO | Mus musculus | GSE133025 | 12,827 | ||
| VDR | kidney | M2-IKO | GEO | Mus musculus | GSE133025 | 52,832 | ||
| VDR | kidney | M2-IKO_veh | GEO | Mus musculus | GSE133025 | 20,534 | ||
| VDR | thyroparathyroid | GEO | Mus musculus | GSE133025 | 8,378 | |||
| VDR | MSC | veh_d15 | GEO | Mus musculus | GSE79813 | 1,031 | ||
| VDR | MSC | 125OH_adipogenic | GEO | Mus musculus | GSE79813 | 3,178 | ||
| VDR | MSC | 125OH | GEO | Mus musculus | GSE79813 | 50,640 | ||
| VDR | MSC | veh_d7 | GEO | Mus musculus | GSE79813 | 358 | ||
| VDR | MSC | veh_adipogenic | GEO | Mus musculus | GSE79813 | 1,327 | ||
| VDR | MSC | 125OH_d15 | GEO | Mus musculus | GSE79813 | 8,527 | ||
| VDR | MSC | 125OH_d7 | GEO | Mus musculus | GSE79813 | 1,856 | ||
| VDR | MC3T3-E1 | GEO | Mus musculus | GSE51513 | 22,053 | |||
| VDR | MC3T3-E1 | veh | GEO | Mus musculus | GSE51513 | 6,709 | ||
| VDR | kidney | veh | GEO | Mus musculus | GSE133025 | 21,107 | ||
| VDR | intestine | GEO | Mus musculus | GSE69179 | 62,556 | |||
| VDR | MSC | veh | GEO | Mus musculus | GSE79813 | 16,238 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |