VDR

Information VDR

Description

Nuclear receptor for calcitriol, the active form of vitamin D3 which mediates the action of this vitamin on cells (By similarity). Enters the nucleus upon vitamin D3 binding where it forms heterodimers with the retinoid X receptor/RXR (By similarity). The VDR-RXR heterodimers bind to specific response elements on DNA and activate the transcription of vitamin D3-responsive target genes (By similarity). Plays a central role in calcium homeostasis (By similarity). {ECO:0000250|UniProtKB:P11473, ECO:0000250|UniProtKB:P13053}.(Source UnitProtKB).

Full Name

vitamin D (1,25-dihydroxyvitamin D3) receptor

Source UniprotKB

Species

Mus musculus [tax_id: 10090]

Genome

mm10

ReMap Statistics

Datasets
24
Biotypes
8
Peaks
411,037
Non-redundant peaks
187,038

TF Classification

Familly
Nuclear receptors with C4 zinc fingers
Sub Familly
Thyroid hormone receptor-related factors (NR1)

Source JASPAR

External IDs

NCBI Gene
22337
Official Gene Name
Vdr
JASPAR
MA0693.1
MGI
MGI:103076
Ensembl
ENSMUSG00000022479
UniProt
P48281
Genevisible
P48281
RefSeq
NM_009504
Aliases
Nr1i1
All peaks VDR
Download BED file
Non redundant peaks VDR
Download BED file
SEQUENCES VDR
Download FASTA file
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Datasets Table for VDR

Target nameTarget modificationEcotype/StrainBiotypeBiotype modificationSourceSpeciesExperimentPeaks
VDR peripheral-blood-monocyte GEO Mus musculus GSE133025 26,763
VDR peripheral-blood-monocyte veh GEO Mus musculus GSE133025 4,089
VDR IDG-SW3 GEO Mus musculus GSE54782 7,189
VDR IDG-SW3 veh GEO Mus musculus GSE54782 610
VDR macrophage GEO Mus musculus GSE124722 7,283
VDR macrophage VD3 GEO Mus musculus GSE124722 39,169
VDR kidney GEO Mus musculus GSE133025 34,834
VDR kidney M1-IKO_veh GEO Mus musculus GSE133025 949
VDR kidney M1-IKO GEO Mus musculus GSE133025 12,827
VDR kidney M2-IKO GEO Mus musculus GSE133025 52,832
Target nameTarget modificationEcotype/StrainBiotypeBiotype modificationSourceSpeciesExperimentPeaks
Showing 1 to 10 of 24 entries