WAPL

Information WAPL

Description

Studies suggest that the protein encoded by this gene is important for the release of cohesin from chromatin. This gene product is thought to be essential for development, and reduced expression of this gene in cells causes defects in chromatin structure. High levels of expression of the human ortholog of this gene are observed in cervical cancers, and expression of the human ortholog of this gene in mice results in tumor formation. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Aug 2014]

Full Name

WAPL cohesin release factor

Source UniprotKB

Species

Mus musculus [tax_id: 10090]

Genome

mm10

ReMap Statistics

Datasets
1
Biotypes
1
Peaks
8,656
Non-redundant peaks
8,656

TF Classification

Familly
NA
Sub Familly
NA

Source JASPAR

External IDs

NCBI Gene
218914
Official Gene Name
Wapl
JASPAR
MGI
MGI:2675859
Ensembl
ENSMUSG00000041408
UniProt
Q65Z40
Genevisible
Q65Z40
RefSeq
NM_001301330
Aliases
A530089A20Rik; Wapal
All peaks WAPL
Download BED file
Non redundant peaks WAPL
Download BED file
SEQUENCES WAPL
Download FASTA file
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Datasets Table for WAPL

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
WAPL mESC GEO Mus musculus GSE63324 8,656
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks