WAPL
Information WAPL
- Description
Studies suggest that the protein encoded by this gene is important for the release of cohesin from chromatin. This gene product is thought to be essential for development, and reduced expression of this gene in cells causes defects in chromatin structure. High levels of expression of the human ortholog of this gene are observed in cervical cancers, and expression of the human ortholog of this gene in mice results in tumor formation. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Aug 2014]
- Full Name
WAPL cohesin release factor
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 1
- Biotypes
- 1
- Peaks
- 8,656
- Non-redundant peaks
- 8,656
TF Classification
- Familly
- NA
- Sub Familly
- NA
Source JASPAR
External IDs
- NCBI Gene
- 218914
- Official Gene Name
- Wapl
- JASPAR
- MGI
- MGI:2675859
- Ensembl
- ENSMUSG00000041408
- UniProt
- Q65Z40
- Genevisible
- Q65Z40
- RefSeq
- NM_001301330
- Aliases
- A530089A20Rik; Wapal