WT1
Information WT1
- Description
This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It plays an essential role in the normal development of the urogenital system, and the orthologous human gene is mutated in a small subset of patients with Wilm's tumors. Alternative splicing has been noted for this gene, however, the full-length nature of these variants is not known. The mRNA for this gene has been shown to initiate translation from non-AUG (CUG) and AUG translation start sites, resulting in different isoforms. [provided by RefSeq, Apr 2013]
- Full Name
Wilms tumor 1 homolog
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 2
- Biotypes
- 1
- Peaks
- 51,851
- Non-redundant peaks
- 41,211
TF Classification
- Familly
- C2H2 zinc finger factors
- Sub Familly
- More than 3 adjacent zinc fingers
Source JASPAR
Datasets Table for WT1
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| WT1 | kidney | E16-5 | GEO | Mus musculus | GSE90016 | 18,188 | ||
| WT1 | kidney | GEO | Mus musculus | GSE64063 | 33,663 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |