YAP1

Information YAP1

Description

This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013]

Full Name

Yes1 associated transcriptional regulator

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
10
Biotypes
10
Peaks
57,933
Non-redundant peaks
44,456

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
10413
Official Gene Name
YAP1
JASPAR
Ensembl
ENSG00000137693
UniProt
P46937
Genevisible
P46937
RefSeq
NM_001130145
Aliases
COB1; YAP; YAP2; YAP65; YKI
All peaks YAP1
Download BED file
Non redundant peaks YAP1
Download BED file
SEQUENCES YAP1
Download FASTA file
DOWNLOAD All ReMap
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Datasets Table for YAP1

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
YAP1 OVCAR-5 GEO Homo sapiens GSE57236 8,914
YAP1 H69 GEO Homo sapiens GSE62274 1,175
YAP1 HUCCT1 GEO Homo sapiens GSE68296 167
YAP1 WA01 GEO Homo sapiens GSE99202 646
YAP1 MCF-10A GEO Homo sapiens GSE97972 12,857
YAP1 MSTO GEO Homo sapiens GSE68170 1,199
YAP1 MDA-MB-231 GEO Homo sapiens GSE66081 15,905
YAP1 MCF-7 GEO Homo sapiens GSE107013 9,114
YAP1 CCLP1 GEO Homo sapiens GSE62272 91
YAP1 hiPSC GEO Homo sapiens GSE111930 7,865
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks