YAP1
Information YAP1
- Description
This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013]
- Full Name
Yes1 associated transcriptional regulator
Source NCBI
- Species
Homo sapiens [tax_id: 9606]
- Genome
hg38
ReMap Statistics
- Datasets
- 10
- Biotypes
- 10
- Peaks
- 57,933
- Non-redundant peaks
- 44,456
TF Classification
- Super Class
- NA
- Class
- NA
- Familly
- NA
- Sub Familly
- NA
Source TFClass
External IDs
- NCBI Gene
- 10413
- Official Gene Name
- YAP1
- JASPAR
- Ensembl
- ENSG00000137693
- UniProt
- P46937
- Genevisible
- P46937
- RefSeq
- NM_001130145
- Aliases
- COB1; YAP; YAP2; YAP65; YKI
Datasets Table for YAP1
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| YAP1 | OVCAR-5 | GEO | Homo sapiens | GSE57236 | 8,914 | |||
| YAP1 | H69 | GEO | Homo sapiens | GSE62274 | 1,175 | |||
| YAP1 | HUCCT1 | GEO | Homo sapiens | GSE68296 | 167 | |||
| YAP1 | WA01 | GEO | Homo sapiens | GSE99202 | 646 | |||
| YAP1 | MCF-10A | GEO | Homo sapiens | GSE97972 | 12,857 | |||
| YAP1 | MSTO | GEO | Homo sapiens | GSE68170 | 1,199 | |||
| YAP1 | MDA-MB-231 | GEO | Homo sapiens | GSE66081 | 15,905 | |||
| YAP1 | MCF-7 | GEO | Homo sapiens | GSE107013 | 9,114 | |||
| YAP1 | CCLP1 | GEO | Homo sapiens | GSE62272 | 91 | |||
| YAP1 | hiPSC | GEO | Homo sapiens | GSE111930 | 7,865 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |