YBX1

Information YBX1

Description

This gene encodes a highly conserved cold shock domain protein that has broad nucleic acid binding properties. The encoded protein functions as both a DNA and RNA binding protein and has been implicated in numerous cellular processes including regulation of transcription and translation, pre-mRNA splicing, DNA reparation and mRNA packaging. This protein is also a component of messenger ribonucleoprotein (mRNP) complexes and may have a role in microRNA processing. This protein can be secreted through non-classical pathways and functions as an extracellular mitogen. Aberrant expression of the gene is associated with cancer proliferation in numerous tissues. This gene may be a prognostic marker for poor outcome and drug resistance in certain cancers. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on multiple chromosomes. [provided by RefSeq, Sep 2015]

Full Name

Y-box binding protein 1

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
5
Biotypes
5
Peaks
22,086
Non-redundant peaks
17,834

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
4904
Official Gene Name
YBX1
JASPAR
Ensembl
ENSG00000065978
UniProt
P67809
Genevisible
P67809
RefSeq
NM_004559
Aliases
BP-8; CBF-A; CSDA2; CSDB; DBPB; EFI-A; MDR-NF1; NSEP-1; NSEP1; YB-1; YB1
All peaks YBX1
Download BED file
Non redundant peaks YBX1
Download BED file
SEQUENCES YBX1
Download FASTA file
DOWNLOAD All ReMap
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Datasets Table for YBX1

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
YBX1 MCF-7 ENCODE Homo sapiens ENCSR864KNH 964
YBX1 K-562 ENCODE Homo sapiens ENCSR107RHZ 1,694
YBX1 Hep-G2 ENCODE Homo sapiens ENCSR799GOY 4,875
YBX1 GM12878 ENCODE Homo sapiens ENCSR205SKQ 3,124
YBX1 HEL GEO Homo sapiens GSE146717 11,429
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks