ZEB1

Information ZEB1

Description

This gene encodes a zinc finger transcription factor. The encoded protein likely plays a role in transcriptional repression of interleukin 2. Mutations in this gene have been associated with posterior polymorphous corneal dystrophy-3 and late-onset Fuchs endothelial corneal dystrophy. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Mar 2010]

Full Name

zinc finger E-box binding homeobox 1

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
10
Biotypes
8
Peaks
155,380
Non-redundant peaks
110,495

TF Classification

Super Class
Helix-turn-helix domains
Class
Homeo domain factors
Familly
HD-ZF factors
Sub Familly
ZEB

Source TFClass

External IDs

NCBI Gene
6935
Official Gene Name
ZEB1
JASPAR
MA0103
Ensembl
ENSG00000148516
UniProt
P37275
Genevisible
P37275
RefSeq
NM_001128128
Aliases
AREB6; BZP; DELTAEF1; FECD6; NIL-2-A; NIL2A; PPCD3; TCF8; ZFHEP; ZFHX1A
All peaks ZEB1
Download BED file
Non redundant peaks ZEB1
Download BED file
SEQUENCES ZEB1
Download FASTA file
DOWNLOAD All ReMap
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Datasets Table for ZEB1

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
ZEB1 RKO GEO Homo sapiens GSE88734 10,207
ZEB1 NCI-H1975 resistant GEO Homo sapiens GSE106896 11,175
ZEB1 NCI-H1975 GEO Homo sapiens GSE106896 4,067
ZEB1 PDAC GEO Homo sapiens GSE64557 18,996
ZEB1 Hep-G2 ENCODE Homo sapiens ENCSR000BVN 13,172
ZEB1 HEK293 ENCODE Homo sapiens ENCSR909HMT 22,109
ZEB1 GM12878 ENCODE Homo sapiens ENCSR000BND 50,629
ZEB1 MIA-PaCa-2 WT GEO Homo sapiens GSE88734 1,125
ZEB1 MIA-PaCa-2 GEO Homo sapiens GSE88734 3,949
ZEB1 neuron bipolar_doxy_4d ENCODE Homo sapiens ENCSR418KUS 19,951
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks