ZFP322A
Information ZFP322A
- Description
Transcriptional activator. Important for maintenance of pluripotency in embryonic stem cells. Binds directly to the POU5F1 distal enhancer and the NANOG proximal promoter, and enhances expression of both genes. Can also bind to numerous other gene promoters and regulates expression of many other pluripotency factors, either directly or indirectly. Promotes inhibition of MAPK signaling during embryonic stem cell differentiation. {ECO:0000269|PubMed:24550733}.(Source UnitProtKB).
- Full Name
zinc finger protein 322A
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 1
- Biotypes
- 1
- Peaks
- 222
- Non-redundant peaks
- 222
TF Classification
- Familly
- NA
- Sub Familly
- NA
Source JASPAR
External IDs
- NCBI Gene
- 218100
- Official Gene Name
- Zfp322a
- JASPAR
- MGI
- MGI:2442566
- Ensembl
- ENSMUSG00000046351
- UniProt
- Q8BZ89
- Genevisible
- Q8BZ89
- RefSeq
- NM_172586
- Aliases
- 9630054P07Rik