ZFP568

Information ZFP568

Description

Has transcriptional repression activity, partially through the recruitment of the corepressor TRIM28 but has also repression activity independently of this interaction (PubMed:22110054, PubMed:27658112). Essential during embryonic development, where it acts as direct repressor of IGF2-P0, placental-specific transcript of IGF2, in early development and regulates convergent extension movements required for axis elongation and tissue morphogenesis in all germ layers (PubMed:18701545, PubMed:22110054, PubMed:28522536). Also important for normal morphogenesis of extraembryonic tissues including the yolk sac, extraembryonic mesoderm and placenta (PubMed:18701545, PubMed:21094155). May enhance proliferation or maintenance of neural stem cells (PubMed:23071813). {ECO:0000269|PubMed:18701545, ECO:0000269|PubMed:21094155, ECO:0000269|PubMed:22110054, ECO:0000269|PubMed:23071813, ECO:0000269|PubMed:27658112}.(Source UnitProtKB).

Full Name

zinc finger protein 568

Source UniprotKB

Species

Mus musculus [tax_id: 10090]

Genome

mm10

ReMap Statistics

Datasets
1
Biotypes
1
Peaks
335
Non-redundant peaks
335

TF Classification

Familly
NA
Sub Familly
NA

Source JASPAR

External IDs

NCBI Gene
243905
Official Gene Name
Zfp568
JASPAR
MGI
MGI:2142347
Ensembl
ENSMUSG00000074221
UniProt
E9PYI1
Genevisible
E9PYI1
RefSeq
NM_001167873
Aliases
LOC381866; chato
All peaks ZFP568
Download BED file
Non redundant peaks ZFP568
Download BED file
SEQUENCES ZFP568
Download FASTA file
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Datasets Table for ZFP568

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
ZFP568 mESC GEO Mus musculus GSE84832 335
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks