ZFP568
Information ZFP568
- Description
Has transcriptional repression activity, partially through the recruitment of the corepressor TRIM28 but has also repression activity independently of this interaction (PubMed:22110054, PubMed:27658112). Essential during embryonic development, where it acts as direct repressor of IGF2-P0, placental-specific transcript of IGF2, in early development and regulates convergent extension movements required for axis elongation and tissue morphogenesis in all germ layers (PubMed:18701545, PubMed:22110054, PubMed:28522536). Also important for normal morphogenesis of extraembryonic tissues including the yolk sac, extraembryonic mesoderm and placenta (PubMed:18701545, PubMed:21094155). May enhance proliferation or maintenance of neural stem cells (PubMed:23071813). {ECO:0000269|PubMed:18701545, ECO:0000269|PubMed:21094155, ECO:0000269|PubMed:22110054, ECO:0000269|PubMed:23071813, ECO:0000269|PubMed:27658112}.(Source UnitProtKB).
- Full Name
zinc finger protein 568
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 1
- Biotypes
- 1
- Peaks
- 335
- Non-redundant peaks
- 335
TF Classification
- Familly
- NA
- Sub Familly
- NA
Source JASPAR
External IDs
- NCBI Gene
- 243905
- Official Gene Name
- Zfp568
- JASPAR
- MGI
- MGI:2142347
- Ensembl
- ENSMUSG00000074221
- UniProt
- E9PYI1
- Genevisible
- E9PYI1
- RefSeq
- NM_001167873
- Aliases
- LOC381866; chato