ZFPM1
Information ZFPM1
- Description
Transcription regulator that plays an essential role in erythroid and megakaryocytic cell differentiation. Essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA1, GATA2 and GATA3. Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context. The heterodimer formed with GATA proteins is essential to activate expression of genes such as NFE2, ITGA2B, alpha- and beta-globin, while it represses expression of KLF1. May be involved in regulation of some genes in gonads. May also be involved in cardiac development, in a non-redundant way with ZFPM2/FOG2. {ECO:0000269|PubMed:10078204, ECO:0000269|PubMed:10329627, ECO:0000269|PubMed:11940669, ECO:0000269|PubMed:12356738, ECO:0000269|PubMed:14614148, ECO:0000269|PubMed:9230307, ECO:0000269|PubMed:9553047}.(Source UnitProtKB).
- Full Name
zinc finger protein, multitype 1
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 3
- Biotypes
- 2
- Peaks
- 51,348
- Non-redundant peaks
- 39,371
TF Classification
- Familly
- NA
- Sub Familly
- NA
Source JASPAR
External IDs
- NCBI Gene
- 22761
- Official Gene Name
- Zfpm1
- JASPAR
- MGI
- MGI:1095400
- Ensembl
- ENSMUSG00000049577
- UniProt
- O35615
- Genevisible
- O35615
- RefSeq
- Aliases
- FOG; Fog1; Friend of GATA-1
Datasets Table for ZFPM1
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| ZFPM1 | T-cell | GEO | Mus musculus | GSE93755 | 14,769 | |||
| ZFPM1 | TSC | differentiated | GEO | Mus musculus | GSE110950 | 16,889 | ||
| ZFPM1 | T-cell | mock | GEO | Mus musculus | GSE93755 | 19,690 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |