ZFX

Information ZFX

Description

This gene on the X chromosome is structurally similar to a related gene on the Y chromosome. It encodes a member of the krueppel C2H2-type zinc-finger protein family. The full-length protein contains an acidic transcriptional activation domain (AD), a nuclear localization sequence (NLS) and a DNA binding domain (DBD) consisting of 13 C2H2-type zinc fingers. Studies in mouse embryonic and adult hematopoietic stem cells showed that this gene was required as a transcriptional regulator for self-renewal of both stem cell types, but it was dispensable for growth and differentiation of their progeny. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2010]

Full Name

zinc finger protein X-linked

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
13
Biotypes
9
Peaks
200,839
Non-redundant peaks
104,340

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
7543
Official Gene Name
ZFX
JASPAR
Ensembl
ENSG00000005889
UniProt
P17010
Genevisible
P17010
RefSeq
NM_001178084
Aliases
ZNF926
All peaks ZFX
Download BED file
Non redundant peaks ZFX
Download BED file
SEQUENCES ZFX
Download FASTA file
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Datasets Table for ZFX

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
ZFX MCF-7 GEO Homo sapiens GSE102616 22,625
ZFX NOMO1 GEO Homo sapiens GSE43147 7,361
ZFX RPMI8402 GEO Homo sapiens GSE43147 812
ZFX HEK293T 22Rv1 GEO Homo sapiens GSE145160 16,905
ZFX HEK293T FLAG GEO Homo sapiens GSE145160 70,017
ZFX MCF-7 ENCODE Homo sapiens ENCSR435OQD 9,778
ZFX K-562 ENCODE Homo sapiens ENCSR920ASP 18,823
ZFX DAOY GEO Homo sapiens GSE45394 8,390
ZFX HCT-116 ENCODE Homo sapiens ENCSR503GVO 11,849
ZFX HCT-116 GEO Homo sapiens GSE102616 11,810
ZFX PrEC GEO Homo sapiens GSE102616 9,046
ZFX LNCaP-C4-2B ENCODE Homo sapiens ENCSR027UFT 6,709
ZFX LNCaP-C4-2B GEO Homo sapiens GSE102616 6,714
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks