ZIC2
Information ZIC2
- Description
This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This protein functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. Expansion of an alanine repeat in the C-terminus of the encoded protein and other mutations in this gene cause holoprosencephaly type 5. Holoprosencephaly is the most common structural anomaly of the human brain. A polyhistidine tract polymorphism in this gene may be associated with increased risk of neural tube defects. This gene is closely linked to a gene encoding zinc finger protein of the cerebellum 5, a related family member on chromosome 13. [provided by RefSeq, Jul 2016]
- Full Name
Zic family member 2
Source NCBI
- Species
Homo sapiens [tax_id: 9606]
- Genome
hg38
ReMap Statistics
- Datasets
- 4
- Biotypes
- 2
- Peaks
- 12,073
- Non-redundant peaks
- 9,758
TF Classification
- Super Class
- NA
- Class
- NA
- Familly
- NA
- Sub Familly
- NA
Source TFClass
Datasets Table for ZIC2
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| ZIC2 | BCBL-1 | latent | GEO | Homo sapiens | GSE102462 | 1,353 | ||
| ZIC2 | BCBL-1 | lytic | GEO | Homo sapiens | GSE102462 | 351 | ||
| ZIC2 | HCT-116 | WT | GEO | Homo sapiens | GSE127960 | 9,287 | ||
| ZIC2 | HCT-116 | C3 | GEO | Homo sapiens | GSE127960 | 1,082 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |