cwo

The gene clockwork orange is referred to in FlyBase by the symbol Dmelcwo (CG17100, FBgn0259938). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3R:10388258..10400752. Its molecular function is described by: protein dimerization activity; DNA-binding transcription factor activity; DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding. It is involved in the biological process described with 9 unique terms, many of which group under: regulation of circadian rhythm; neuron projection morphogenesis; pattern specification process; neuron development; regulation of developmental process. 25 alleles are reported. The phenotypes of these alleles manifest in: abdominal anterior ventral multidendritic neuron vdaa; larval dorsal multidendritic neuron ddaD; larval dorsal multidendritic neuron ddaC; wing. The phenotypic classes of alleles include: phenotype; circadian rhythm defective; increased mortality; increased mortality during development. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 12-24 hour embryonic stages, during early larval stages, in adult female stages.

clockwork orange

Source FlyBase

Drosophila melanogaster [tax_id: 7227]

dm6