en

The gene engrailed is referred to in FlyBase by the symbol Dmelen (CG9015, FBgn0000577). It is a protein_coding_gene from Dmel. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:11524006..11528210. Its molecular function is described by: DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding; sequence-specific DNA binding. It is involved in the biological process described with 25 unique terms, many of which group under: compartment pattern specification; morphogenesis of an epithelium; tube morphogenesis; embryo development; analia development. 168 alleles are reported. The phenotypes of these alleles manifest in: female reproductive gland; mesodermal derivative; external compound sense organ; primary neuron; germ layer. The phenotypic classes of alleles include: increased mortality; phenotype; embryonic/larval segmentation phenotype; fertile. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 00-12 hour embryonic stages.

engrailed

Source FlyBase

Drosophila melanogaster [tax_id: 7227]

dm6