fkh

The gene fork head is referred to in FlyBase by the symbol Dmelfkh (CG10002, FBgn0000659). It is a protein_coding_gene from Dmel. It has 5 annotated transcripts and 5 polypeptides (3 unique). Gene sequence location is 3R:28580976..28585264. Its molecular function is described by: RNA polymerase II transcription regulatory region sequence-specific DNA binding; protein domain specific binding; transcription factor binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific. It is involved in the biological process described with 18 unique terms, many of which group under: gland morphogenesis; negative regulation of cellular macromolecule biosynthetic process; multicellular organism growth; endoderm development; DNA-dependent DNA replication. 34 alleles are reported. The phenotypes of these alleles manifest in: ectodermal derivative; mesodermal derivative; embryonic/larval midgut primordium; non-connected functional system; embryonic foregut. The phenotypic classes of alleles include: visible; cell size defective; phenotype; increased mortality during development. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression. Peak expression observed within 06-12 hour embryonic stages.

fork head

Source FlyBase

Drosophila melanogaster [tax_id: 7227]

dm6