foxo

The gene forkhead box, sub-group O is referred to in FlyBase by the symbol Dmelfoxo (CG3143, FBgn0038197). It is a protein_coding_gene from Dmel. It has 5 annotated transcripts and 5 polypeptides (3 unique). Gene sequence location is 3R:14056945..14087978. Its molecular function is described by 6 unique terms, many of which group under: DNA-binding transcription factor activity; transcription regulator activity; binding; regulatory region nucleic acid binding; molecular function regulator. It is involved in the biological process described with 41 unique terms, many of which group under: response to nutrient levels; aging; negative regulation of growth; developmental growth; compound eye development. 78 alleles are reported. The phenotypes of these alleles manifest in: appendage; myoblast; adult circulatory system; embryonic/larval adipose system; synaptic vesicle. The phenotypic classes of alleles include: body size defective; phenotype; increased mortality; stress response defective. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 and 18-24 hour embryonic stages, during late pupal stages.

forkhead box, sub-group O

Source FlyBase

Drosophila melanogaster [tax_id: 7227]

dm6