gcm

The gene glial cells missing is referred to in FlyBase by the symbol Dmelgcm (CG12245, FBgn0014179). It is a protein_coding_gene from Dmel. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:9579498..9581745. Its molecular function is described by: DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding. It is involved in the biological process described with 22 unique terms, many of which group under: vesicle-mediated transport; regulation of glial cell proliferation; head development; dendrite morphogenesis; positive regulation of glial cell differentiation. 67 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval glial cell; posterior commissure; acellular anatomical structure; abdominal intersegmental nerve neuron; dendritic tree. The phenotypic classes of alleles include: increased mortality; cell number defective; lethal - all die before end of pupal stage; phenotype. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed within 00-18 hour embryonic stages.

glial cells missing

Source FlyBase

Drosophila melanogaster [tax_id: 7227]

dm6