grh

The gene grainy head is referred to in FlyBase by the symbol Dmelgrh (CG42311, FBgn0259211). It is a protein_coding_gene from Dmel. It has 8 annotated transcripts and 8 polypeptides (7 unique). Gene sequence location is 2R:17801132..17842820. Its molecular function is described by 6 unique terms, many of which group under: DNA binding; nucleic acid binding; binding; DNA-binding transcription factor activity; heterocyclic compound binding. It is involved in the biological process described with 18 unique terms, many of which group under: cellular response to organic substance; cell population proliferation; photoreceptor cell fate commitment; epithelial cell differentiation; chitin-based embryonic cuticle biosynthetic process. 57 alleles are reported. The phenotypes of these alleles manifest in: cuticle layer; denticle field; embryonic/first instar larval cuticle; cell-cell junction; adult neuron. The phenotypic classes of alleles include: increased mortality during development; partially lethal; lethal; phenotype. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the pupal period.

grainy head

Source FlyBase

Drosophila melanogaster [tax_id: 7227]

dm6