hth

Information hth

Description

The gene homothorax is referred to in FlyBase by the symbol Dmelhth (CG17117, FBgn0001235). It is a protein_coding_gene from Dmel. It has 5 annotated transcripts and 5 polypeptides (4 unique). Gene sequence location is 3R:10507561..10639568. Its molecular function is described by 9 unique terms, many of which group under: binding; molecular function regulator; protein binding; transcription regulator activity; DNA-binding transcription factor activity. It is involved in the biological process described with 27 unique terms, many of which group under: post-embryonic animal organ morphogenesis; segmentation; positive regulation of transcription by RNA polymerase II; body morphogenesis; specification of segmental identity, antennal segment. 93 alleles are reported. The phenotypes of these alleles manifest in: late embryo; bract; abdominal tergite 3; periphallic sclerite; embryonic/larval excretory system. The phenotypic classes of alleles include: phenotype; viable; some die during larval stage; increased mortality. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 00-18 hour embryonic stages, during late larval stages, during early pupal stages.

Full Name

homothorax

Source FlyBase

Species

Drosophila melanogaster [tax_id: 7227]

Genome

dm6

ReMap Statistics

Datasets
4
Biotypes
2
Peaks
31,238
Non-redundant peaks
22,800

TF Classification

Familly
Homeo domain factors
Sub Familly
TALE-type homeo domain factors

Source JASPAR

External IDs

NCBI Gene
41273
Official Gene Name
hth
JASPAR
MA0227.1
Ensembl
FBgn0001235
UniProt
O46339
Genevisible
O46339
RefSeq
NM_057230
Aliases
hth
All peaks hth
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Non redundant peaks hth
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SEQUENCES hth
Download FASTA file
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Datasets Table for hth

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
hth adult wing GEO Drosophila melanogaster GSE125604 5,541
hth adult whole-fly ENCODE Drosophila melanogaster ENCSR249JVE 8,129
hth Kc167 GEO Drosophila melanogaster GSE122574 7,192
hth Kc167 stable GEO Drosophila melanogaster GSE122573 10,376
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks