lab

The gene labial is referred to in FlyBase by the symbol Dmellab (CG1264, FBgn0002522). It is a protein_coding_gene from Dmel. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:6661427..6678590. Its molecular function is described by: DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding; cis-regulatory region sequence-specific DNA binding; protein heterodimerization activity. It is involved in the biological process described with 8 unique terms, many of which group under: developmental process; anatomical structure development; nervous system development; cell differentiation; central nervous system development. 42 alleles are reported. The phenotypes of these alleles manifest in: appendage segment; embryonic/larval gut; salivary gland; cluster of actin-based cell projections; longitudinal connective. The phenotypic classes of alleles include: viable; lethal; lethal - all die before end of second instar larval stage; increased mortality during development. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed within 12-24 hour embryonic stages, during early larval stages.

labial

Source FlyBase

Drosophila melanogaster [tax_id: 7227]

dm6