mle

The gene maleless is referred to in FlyBase by the symbol Dmelmle (CG11680, FBgn0002774). It is a protein_coding_gene from Dmel. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:5974857..5980778. Its molecular function is described by 11 unique terms, many of which group under: heterocyclic compound binding; organic cyclic compound binding; RNA binding; pyrophosphatase activity; helicase activity. It is involved in the biological process described with 12 unique terms, many of which group under: negative regulation of biological process; reproductive process; neuron projection morphogenesis; organonitrogen compound biosynthetic process; regulation of catalytic activity. 62 alleles are reported. The phenotypes of these alleles manifest in: appendage; spermatozoon; chromosome; organelle; region. The phenotypic classes of alleles include: phenotype; some die during larval stage; partially lethal; increased mortality. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages, at stages throughout the pupal period.

maleless

Source FlyBase

Drosophila melanogaster [tax_id: 7227]

dm6