sage

The gene salivary gland-expressed bHLH is referred to in FlyBase by the symbol Dmelsage (CG12952, FBgn0037672). It is a protein_coding_gene from Dmel. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:9262654..9264142. Its molecular function is described by: protein dimerization activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific; DNA-binding transcription factor activity. It is involved in the biological process described with: salivary gland development; regulation of transcription by RNA polymerase II; positive regulation of transcription by RNA polymerase II; regulation of transcription, DNA-templated; mesoderm formation. 13 alleles are reported. The phenotypes of these alleles manifest in: wing; embryonic/larval salivary gland. The phenotypic classes of alleles include: visible; lethal; increased cell death. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed during late larval stages.

salivary gland-expressed bHLH

Source FlyBase

Drosophila melanogaster [tax_id: 7227]

dm6