tio

The gene tiptop is referred to in FlyBase by the symbol Dmel io (CG12630, FBgn0028979). It is a protein_coding_gene from Dmel. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:22019208..22025734. Its molecular function is described by: DNA-binding transcription factor activity, RNA polymerase II-specific; DNA binding. It is involved in the biological process described with 6 unique terms, many of which group under: system development; epidermis development; anatomical structure development; Malpighian tubule stellate cell differentiation; negative regulation of metabolic process. 22 alleles are reported. The phenotypes of these alleles manifest in: somatic cell; larval thorax; integumentary system; portion of tissue; denticle. The phenotypic classes of alleles include: short lived; lethal - all die during embryonic stage; lethal; viable; visible; fertile. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed within 12-18 embryonic stages, at stages throughout the pupal period, in adult male stages.

tiptop

Source FlyBase

Drosophila melanogaster [tax_id: 7227]

dm6