twi

Information twi

Description

The gene twist is referred to in FlyBase by the symbol Dmel wi (CG2956, FBgn0003900). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2R:22985374..23048325. Its molecular function is described by: DNA binding; RNA polymerase II transcription regulatory region sequence-specific DNA binding; protein heterodimerization activity; DNA-binding transcription factor activity, RNA polymerase II-specific; protein homodimerization activity. It is involved in the biological process described with 16 unique terms, many of which group under: regulation of biological process; cell-cell signaling; cellular component organization or biogenesis; Malpighian tubule morphogenesis; regulation of cellular process. 47 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval muscle system; presumptive embryonic/larval digestive system; midgut primordium; endodermal derivative; foregut. The phenotypic classes of alleles include: increased mortality; increased mortality during development; lethal - all die before end of pupal stage; phenotype. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of very low expression. Peak expression observed within 00-06 hour embryonic stages.

Full Name

twist

Source FlyBase

Species

Drosophila melanogaster [tax_id: 7227]

Genome

dm6

ReMap Statistics

Datasets
3
Biotypes
2
Peaks
77,865
Non-redundant peaks
52,120

TF Classification

Familly
Basic helix-loop-helix factors (bHLH)
Sub Familly

Source JASPAR

External IDs

NCBI Gene
37655
Official Gene Name
twi
JASPAR
MA0249.2
Ensembl
FBgn0003900
UniProt
P10627
Genevisible
P10627
RefSeq
NM_079092
Aliases
twi
All peaks twi
Download BED file
Non redundant peaks twi
Download BED file
SEQUENCES twi
Download FASTA file
DOWNLOAD All ReMap
Got to catalogue

Datasets Table for twi

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
twi adult whole-fly_site-specific-recombination_insertion ENCODE Drosophila melanogaster ENCSR119OUI 23,695
twi embryo 2h-4h-AEL_homemade GEO Drosophila melanogaster GSE55306 37,335
twi embryo tl10b GEO Drosophila melanogaster GSE68983 16,835
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks