wek

The gene weckle is referred to in FlyBase by the symbol Dmelwek (CG4148, FBgn0001990). It is a protein_coding_gene from Dmel. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:15766133..15768349. Its molecular function is described by 6 unique terms, many of which group under: binding; protein binding; DNA binding; DNA-binding transcription factor activity; zinc ion binding. It is involved in the biological process described with: dorsal/ventral axis specification; regulation of transcription by RNA polymerase II; activation of innate immune response; Toll signaling pathway; maternal specification of dorsal/ventral axis, oocyte, germ-line encoded. 22 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval nervous system; anatomical structure; epithelium; integumentary system; organ system. The phenotypic classes of alleles include: phenotype; increased mortality; cell death defective; lethal - all die before end of P-stage. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-12 hour embryonic stages, in adult female stages.

weckle

Source FlyBase

Drosophila melanogaster [tax_id: 7227]

dm6